There is no Federal Motor Carrier Safety Regulation that prohibits a firearm from being possessed by a commercial vehicle operator while driving a commercial vehicle. There might be another law or regulation that prohibits this act depending on who the operator is and what jurisdiction the operator is in.
School contractors need to be in compliance with all CDL driver qualification requirements and regulations (FMCSR 391). It should be noted while there is an exemption for "to and from school" operation, there is no such exemption for trips performed by contractors. School transportation performed by a state or political subdivision of a state (i.e., municipalities) are exempt from some CDL requirements.
Title VI, one section among eleven other titles contained within the Civil Rights Act of 1964, is a federal law providing that:
"No person in the United States shall, on the grounds of race, color, or national origin, be excluded from participation in, be denied the benefit of, or be subjected to discrimination under any program or activity receiving federal financial assistance."
42 U.S.C. 2000d Subsequent federal legislation has led to further protections under Title VI based upon age, gender, and disability, whether mental or physical.
If you are subject to the Federal Motor Carrier Safety Regulations, you must have a physical every two years.
To have a hazardous materials endorsement, you must meet the Federal Motor Carrier Safety regulations except for age requirements for intrastate travel.
Physical must be performed by a nationally certified examiner.